Imizol®

COMPOSITION

Contains: Imidocarb dipropionate 12 % m/v

POISONOUS

STORAGE INSTRUCTIONS

• Store between 2 °C to 25 °C.
• Protect from light.

WARNINGS

• Withdrawal periods:

Milk – 6 days.

Meat – 213 days.

• Imizol® should only be used for preventive purposes in consultation with a veterinarian who must be fully conversant with local conditions pertaining to redwater infections/control, as well as tick control for the area, farm or herd involved.
• Imizol® is not recommended for use after the expiry date (2 years after date of manufacture) as it may be ineffective and may even be harmful to the animal.
• Under certain circumstances of high challenge, virulent strains of Asiatic redwater cases may develop as early as 18 days after administering Imizol®.
• Vaccine warning: After treatment with Imizol® (2,5 mℓ/100 kg body mass) cattle cannot be effectively vaccinated against Asiatic redwater for 8 weeks and against African redwater for 16 weeks.
• Note to physician: This product in animal studies has been shown to be nephrotoxic and this should be borne in mind in the treatment of humans following accidental injection.
• Antidote: No specific antidotes exist. Symptomatic treatment is indicated.
• Dispose of empty containers according to local waste disposal regulations and do not reuse for any other purpose.
• KEEP OUT OF REACH OF CHILDREN, UNINFORMED PERSONS AND ANIMALS.
• Although this product has been extensively tested under a large variety of conditions, failure thereof may ensue as a result of a wide range of reasons. If this is suspected, seek veterinary advice and notify the registration holder.

PRECAUTIONS

• Sterilise all injection apparatus and use a new clean sharp needle for each animal.
• Swab the rubber seal of the bottle with methyl­ated spirit immediately before puncturing with a needle.
• A swelling may occur at the injection site in some animals. These disappear without forming abscesses.
• There may be slight salivation after treatment.
• The dose must be administered strictly accord­ing to body mass and must not be exceeded.
• Take care to avoid accidental injection of opera­tors.

DIRECTIONS FOR USE – USE ONLY AS DIRECTED

Shake well before use.

Redwater	Tick-borne gall sickness
Therapy (treatment)	Therapy (treatment)
1 mℓ/100 kg body mass; administer once only	2,5 mℓ/100 kg body mass; administer once only
Prophylaxis (prevention)
2,5 mℓ/100 kg body mass; administer once only

DOSAGE

Do not repeat the dose within 4 weeks

Administration

• The dose rate must not be exceeded, and the treatment must not be repeated within 4 weeks. If there is no improvement within 24 hours con­sult your veterinarian.
• Inject subcutaneously or intramuscularly only (neck region or areas of least value).
• MUST NOT BE USED INTRAVENOUSLY.

Examples of the use of Imizol® for prevention of redwater

NB: Only on the advice and recommendation of a veterinarian for each set of circumstances.

• Outbreak of redwater in a herd.
• Movement of susceptible cattle into tick areas.
• Movement of susceptible animals through a redwater area.
• Movement of a herd of tick infested cattle into tick free country containing clean susceptible cattle.
• Purchase of cattle of unknown origin, i.e., suscep­tible or carrier cattle.
• Animals taken to shows or sales where there is a risk of redwater.
• To reduce the losses from redwater in feedlot cattle on their introduction.

PRESENTATION

10 mℓ, 40 mℓ and 100 mℓ neutral amber bottles, each closed with grey bromobutyl rubber stopper, silver aluminium collar and flip-top seal covered with a green polypropylene cap.

REGISTRATION HOLDER

Intervet South Africa (Pty) Ltd.

20 Spartan Road, Spartan

1619, RSA

Tel:  + 27 (0) 11 923 9300

E-mail: msdahza@msd.com

www.msd-animal-health.co.za

DATE OF PUBLICATION OF THIS PACKAGE INSERT

28 October 2013