Nobilis® EDS

Nobilis® EDS is an inactivated vaccine for the protection of layers and breeding chickens against Egg Drop Syndrome ’76.

FOR ANIMAL USE ONLY
NOBILIS® EDS
Reg. No. G2578 (Act 36/1947)

INDICATIONS
Nobilis® EDS is an inactivated vaccine for the protection of layers and breeding chickens against Egg Drop Syndrome ’76.

COMPOSITION
Contains the formalin inactivated Egg Drop Syndrome ’76 virus (strain BC 14) antigen.

CONTENTS
Each dose of 0,5 mℓ contains the inactivated EDS ’76 virus (strain BC 14) inducing 6,5 log2 HI units. The virus has been inactivated with formalin and subsequently suspended in the water phase of a water-in-oil emulsion.

STORAGE

  • Store in the dark between 2 °C and 8 °C.
  • Do not freeze.
  • Allow the vaccine to gradually reach room temperature between 20 °C and 25 °C before use.
  • Avoid prolonged or repetitive exposure to high ambient temperatures following withdrawal from the refrigerator prior to use.
  • Protect from direct sunlight.

WARNINGS

  • Withdrawal period: Do not market chickens for slaughter purposes for at least 6 weeks after vaccination.
  • Ensure that chickens marketed do not have swellings at the site of vaccine administration, as this may result in the condemnation of the chickens.
  • Vaccinate healthy chickens only.
  • Opened bottles should be used within 24 hours.
  • Do not store partially used containers for future use and use the entire contents when opened.
  • Do not mix Nobilis® EDS with other vaccines.
  • Vaccination of chickens in production may lead to a slight drop in egg production.
  • Accidental self-vaccination may lead to severe local allergic reaction. Consult a physician informing him/her that the vaccine contains a mineral oil.
  • Destroy any unused vaccine and dispose of all empty vaccine containers as per local waste disposal regulations after vaccination.
  • KEEP OUT OF REACH OF CHILDREN, UNINFORMED PERSONS AND ANIMALS.
  • Although this vaccine has been extensively tested under a large variety of conditions, failure thereof may ensue as a result of a wide range of reasons. If this is suspected, seek veterinary advice and notify the registration holder.

PRECAUTIONS

  • Observe aseptic precautions. Ensure that all vaccination equipment (needles, syringes, etc.) are clean and sterile prior to use.
  • Ensure that all equipment is kept clean and sterile during vaccination.
  • Avoid intravenous injection.
  • It is essential to adhere to the vaccination program to maintain a satisfactory immune response.
  • It is good vaccination practice when handling the vaccine to avoid contact with the eyes, hands and clothing.

DIRECTIONS FOR USE – USE ONLY AS DIRECTED
Recommended Vaccination Programme

  • Nobilis® EDS should be given to chickens around 16 to 20 weeks of age, but not less than 4 weeks before the expected onset of lay.
  • Allow the vaccine to gradually reach room temperature between 20 °C and 25 °C before use.
  • Shake well before use and at regular intervals during the vaccination process.
  • Remove the aluminium overseal and the vaccine is ready for use.

DOSAGE AND ADMINISTRATION

  • Each chicken should be given 0,5 mℓ of the vaccine intramuscularly into the breast muscle or subcutaneously in the lower part of the neck. (Intramuscular injection into the breast muscle: The needle should be pointed in the direction of the chicken’s head to prevent the needle from entering the body cavity).
  • Inject all the chickens in the flock.

VACCINATION REACTIONS
In healthy chickens, no clinical reaction to the vaccination will be observed. For some weeks after vaccination a slight swelling may be felt at the site of the vaccination. This does not constitute permanent damage of the tissue provided the vaccination has been carried out aseptically.

PRESENTATION
Bottles containing 500 mℓ sufficient for 1 000 doses.

REGISTRATION HOLDER                                        

Intervet South Africa (Pty) Ltd.
20 Spartan Road, Spartan
1619, RSA
Tel: +27 (0) 11 923 9300
Fax: +27 (0) 11 392 3158
www.msd-animal-health.co.za

MANUFACTURER
Intervet International B.V.

DATE OF PUBLICATION OF THIS PACKAGE INSERT

27 March 2003
35 Wim de Körverstraat
Boxmeer, The Netherlands

Zimbabwe Reg. No. 95/80.23.10/9396 Pharmacological classification: 802310 Distribution category: VMGD