Panacur® Aquasol

For the treatment and control of gastrointestinal nematodes in pigs infected with Ascaris suum (adult, intestinal and migrating larval stages).

FOR ANIMAL USE ONLY

PANACUR® AQUASOL

Reg. No. G4316 (Act 36/1947)

Oral suspension for use in drinking water for pigs and chickens

INDICATIONS

For the treatment and control of gastrointestinal nematodes in pigs, infected with Ascaris suum (adult, intestinal and migrating larval stages), Oesophagostomum spp. (adult stages), Hyostrongylus rubidus (adult and larval stages) and Trichuris suis (adult stages) and in chickens infected with Ascaridia galli, Heterakis gallinarum and Capillaria spp. (pre-adult and adult stages). Panacur® AquaSol has an ovicidal effect on nematode eggs.

COMPOSITION

Contains:Fenbendazole 200 mg/mℓ

Preservative: Benzyl alcohol 20 mg/mℓ

*Benzimidazoles and probenzimidazoles

CAUTION

STORAGE INSTRUCTIONS

  • Store below 30 °C.
  • Do not freeze.
  • After first opening the immediate packaging, use within 6 months.
  • Use the medicated water within 24 hours.
  • Do not use after the expiry date which is stated on the container label.

WARNINGS

  • Withdrawal period: Pigs                   – 4 days meat and offal.

                                            Chickens          – 6 days for meat and offal at 1 mg/kg.

                                                                       -9 days for meat and offal at 2 mg/kg.

                                            Eggs                  – zero days.

  • Parasitic resistance to any particular class of anthelmintic may develop, following frequent, repeated use of an anthelmintic of that class.
  • Can be used during pregnancy and lactation.
  • In the absence of compatibility studies, Panacur® AquaSol must not be mixed with other veterinary medicinal products.
  • KEEP OUT OF REACH OF CHILDREN, UNINFORMED PERSONS AND ANIMALS.
  • Although this remedy has been extensively tested under a large variety of conditions, failure thereof may ensue as a result of a wide range of reasons. If this is suspected, seek veterinary advice and notify the registration holder.

SPECIAL PRECAUTIONS TO BE TAKEN BY THE PERSON ADMINISTERING PANACUR® AQUASOL TO ANIMALS

  • Panacur® AquaSol may cause hypersensitivity reactions. Consult your veterinarian.
  • Wear protective gloves while handling Panacur® AquaSol.
  • Direct contact with Panacur® AquaSol should be avoided. Wash hands after use.
  • In case of skin and/or eye contact, immediately rinse eyes with plenty of water.
  • Dispose of any containers, disposable equipment and any other waste after use, in accordance with National Environmental Management: Waste Act, 2008 (Act No. 59 of 2008) and do not reuse for any other purpose.
  • Panacur® AquaSol should not enter water sources as it is dangerous to aquatic organisms.

DIRECTIONS FOR USE – USE ONLY AS DIRECTED

  • Shake well before use.
  • For use in drinking water.
  • To ensure administration of the correct dose, body weight should be determined as accurately as possible; accuracy of the dosing device should be checked.

DOSAGE

Pigs

The dose is 2,5 mg fenbendazole/kg body weight/day (equivalent to 0,0125 mℓ Panacur® AquaSol). For the treatment and control of Ascaris suum, Oesophagostomum spp. and Hyostrongylus rubidus, this dose must be administered for 2 consecutive days. For the treatment and control of Trichuris suis, this dose must be administered for 3 consecutive days.

Dose calculation:

The required daily amount of product is calculated from the total estimated body weight (kg) of the entire group of pigs to be treated. Please use the following formula:

Amount of product/day in mℓ = Total estimated body weight (kg) of pigs to be treated x 0,0125 mℓ.

Example

Total body weight of pigs to be treatedDay 1 amount of productDay 2 amount of productDay 3 amount of productTotal amount of product (for 2 days)Total amount of product (for 3 days)
80 000 kg1 000 mℓ1 000 mℓ1 000 mℓ2 x 1 000 mℓ3 x 1 000 mℓ
320 000 kg4 000 mℓ4 000 mℓ4 000 mℓ2 x 4 000 mℓ3 x 4 000 mℓ

Chickens

Acaridia galli and Heterakis gallinarum: The dose is 1 mg fenbendazole/kg body weight/day (equivalent to 0,005 mℓ Panacur® AquaSol). This dose must be administered for 5 consecutive days.

Capillaria spp: The dose is 2 mg fenbendazole/kg body weight/day (equivalent to 0,01 mℓ Panacur® AquaSol). This dose must be administered for 5 consecutive days.

Dose calculation:

The required daily amount of product is calculated from the total estimated body weight (kg) of the entire group of chickens to be treated. Please use the following formula:

Amount of product/day in mℓ = Total estimated body weight (kg) of chickens to be treated x 0,005 mℓ for Acaridia galli and Heterakis gallinarum.

Amount of product/day in mℓ = Total estimated body weight (kg) of chickens to be treated x 0,01 mℓ for Capillaria spp.

Example

Total body weight of chickens to be treatedAmount of product per day for 1 mg/kg/day (mℓ/day)Total amount of product (mℓ/for 5 days)Amount of product per day for 2 mg/kg/day (mℓ/day)Total amount of product (mℓ/for 5 days)
40 000 kg200 mℓ1 000 mℓ (5 x 200 mℓ)400 mℓ2 000 mℓ (5 x 400 mℓ)
160 000 kg800 mℓ4 000 mℓ (5 x 800 mℓ)1 600 mℓ8 000 mℓ (5 x 1 600 mℓ)

ADVICE ON CORRECT ADMINISTRATION

  • Before allowing animals to have access to the medicated water, the water delivery system should be drained if possible and flushed with the medicated water to ensure accuracy of dosing. This procedure may need to be performed on all treatment days.
  • Follow the instructions in the order described below to prepare the medicated water. Use a sufficiently accurate measuring device, which should be properly cleaned after use.
  • For each treatment day the medicated water needs to be freshly prepared.
  • Prepare a predilution of Panacur® AquaSol with an equal amount of water:
  • Select a measuring device that has at least double volume of the calculated daily Panacur® AquaSol volume.
  • Pour a volume of water equal to the calculated volume of Panacur® AquaSol needed into the measuring device.
  • Shake Panacur® AquaSol well before mixing.
  • Fill up the measuring device containing the water with the calculated volume of Panacur® AquaSol to obtain the predilution.
  • Add the obtained predilution to the water supply system as described below.

For use in medication tank

  • Add the entire contents of the measuring device (predilution) to the volume of drinking water usually consumed by the animals between 3 and 24 hours.
  • Stir until contents in the medicated tank is visibly homogeneous. The medicated water will appear hazy. No further stirring during administration is necessary.

For use in dosing pump

  • Add the entire contents of the measuring device (predilution) to the unmedicated water in the stock suspension container of the dosing pump. The volume of unmedicated water in the stock suspension container must be calculated, taking as a basis, the preset injection rate of the dosing pump and the volume of drinking water usually consumed by the animals between 3 and 24 hours.
  • Stir until contents in the stock suspension container is visibly homogeneous. The medicated water will appear hazy.
  • For all concentrations of up to 5 mℓ/ℓ stock suspension (1 g fenbendazole/ℓ), no stirring is required.
  • At concentrations above 5 mℓ/ℓ up to 75 mℓ/ℓ stock suspension (15 g fenbendazole/ℓ) and within an 8-hour administration period, no stirring of the stock suspension is required. If the administration period exceeds 8 hours, but being no longer than 24 hours, the stock suspension container needs to be equipped with a stirring device.
  • During treatment all pigs or chickens must have solely but unrestricted access to the medicated water.
  • During treatment, after complete consumption of the medicated water, the pigs or chickens must be allowed access to unmedicated water as soon as possible.
  • Ensure that the total amount of medicated water offered is consumed.

PRESENTATION

White to off-white oral suspension, filled into a clear 1 ℓ or 4 ℓ high density polyethylene (HDPE) container with a thermo seal and closed with a red propylene child-resistant, screw cap.

The 4 ℓ container is provided with a separate polyethylene dispenser (aeroflow tap).

Not all pack sizes may necessarily be marketed.

REGISTRATION HOLDER                                      

Intervet South Africa (Pty) Ltd.                           

20 Spartan Road, Spartan                                      

1619, RSA                                                                      

Tel: +27 (0) 11 923 9300                                          

E-mail: msdahza@msd.com

www.msd-animal-health.co.za

DATE OF PUBLICATION OF THIS PACKAGE INSERT

15 August 2024

Zimbabwe Reg. No. 2017/80.12.10/9768

Pharmacological classification: 801210

Distribution category: VMGD  

SLEGS VIR DIEREGEBRUIK